facts about retinoids – Beyond50skin

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June 9, 2021

11 min
3 years
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Tagged beginner retinols, choosing a retinod, facts about retinoids, how do retinoids work, How do retinol work

5 STEPS TO RETINOID SUCCESS: The Research & The Myths | How to Limit Irritation | When & How Do I Start?

Prevention is worth a pound of cure. Especially when it comes to fine lines, dullness and photo aging! If you’re very lucky […]

RETINOID DERIVATIVES (least to most irritating/effective)	DESCRIPTION	RECOMMENDATIONS (Clickable links)
RETINOIC ESTERS: – Retinyl acetate & linoleate – Hydroxypinacolone Retinoate – Retinyl Palmitate – Retinyl Propionate	Newer, less irritating retinoid derivatives, several steps to convert to retinoic acid, fewest studies on their effectiveness for anti-aging benefits	https://shoplist.us/collections/11109
– Hydroxypinacolone Retinoate (HPR) / Granactive Retinoid	Unique Retinoic ester – binds directly to retinoid receptors. Less irritating than retinol. Tolerated around eyes area at .2%. More RCT studies need.
RETINYL RETINOATE	Retinol – Retinoic Acid hybrid
RETINOL	Easily found in cosmetic formulas, requires two conversions to retinoic acid, well tolerated up to .03%,	https://shoplist.us/collections/11107
RETINALDEHYDE/Retinal	One conversion to retinoic acid, studies show it can be similarly as effective as retinoid acid	https://shoplist.us/collections/10984
ADAPALENE – Differin	Synthetic retinoid derivative, regulates hyperkeratinization, desensitizes skin to inflammation, addresses acne and to a lesser extent photo-aging	https://shoplist.us/collections/10984
RETINOIC ACID Rx – Retin A, Renova, Atralin, Refissa – Tretinoin (generic)	Most bioavailable retinoid for epidermal turnover, disperses melanin, 20 X more potent than retinol. FDA approved, well studied.	Rx
TAZAROTENE Rx – Tazorac, Zorac, Avage – Tazarotene (generic)	Synthetic retinoid, often used for psoriasis, acne vulgaris and less often for photo-aging	Rx
TRIFAROTENE Rx – Aklief	Approved by the FDA in 2020 for acne, potentially less irritating, more tolerable on neck & décolleté	Rx
ISOTRETINOIN Rx – Accutane	High potency oral vitamin A prescribed for cystic acne	Rx